MIS&S Designs Medical Technologies to Prolong Life by Twenty Years

A National University of Science and Technology “MIS&S” research group led by Sergey Prokoshkin and the Endogene-Globetek company (Australia) will present an innovative technology of shape memory alloy and superelasticity usage, as well as prototypes of medical devices and technologies made on its basis.

The high-tech technologies, based on the fundamental properties of certain metals to restore the original shape after an abnormally large deformation, provided the potential to design a variety of unique medical devices and instruments for neurosurgery, pediatrics, cardiovascular surgery, and emergency rescue care.

According to Sergey Prokoshkin, Doctor of Physical and Mathematical Sciences, professor of special alloy plastic deformation, and Research Group Head at the National University of Science and Technology “MIS&S,” "The fundamental basis of the shape memory effect was discovered by Georgiy Kurdyumov, outstanding Soviet physicist, and Leo Khandros, his student, in 1948. Shape memory has two kinds of activity: a shape memory effect due to the form restored after deformation during subsequent heating and a superelasticity effect due to the form restored after deformation during unloading. A unique functional property of shape memory alloys is reversible deformation (up-to-10%). It provides opportunities not achievable using conventional materials and technologies."

The general advantages of all presented technologies lie in the fact that they are easy to use and allow surgery interference in a quick and reliable way with minimal risk to the patient. Through the use of innovative equipment it is possible to reduce the cost of operations several times over because it allows the use of non-invasive methods and does not require anesthesia.

The self-propelled endoscopic device for ballooning and stenting of intestine tract restrictions is the most revolutionary technology, which has no analogues in the world. The endoscope allows a quick survey of the entire gastrointestinal tract, including the small intestine, which existing tools do not provide. It can help you swiftly and successfully diagnose bowel cancer, cure adhesive disease, and Crohn's disease, which is becoming more common in developed countries, as well as quickly extracting toxins from the intestines. And all this can be done without anesthesia or surgical operations.

The cardiovascular stapler is one of the new generation cross-linking tools that allow the user to quickly perform surgical operations on cardiovascular diseases, which are still “the top killers" among all diseases. The stapler allows performing surgical operations, such ascoronary artery bypass, without stopping the heart by non-invasive methods: two punctures in the heart areaenables discharging the patient from hospital in a day. The duration of this procedure, together with the preparation, is one hour while such operations now can take from four to five hours. This operation on the heart may add twenty years to a person’s life.

The stapler may also be used during an aortic aneurysm and intestinal and abdominal surgeries .
The surgical smart clip and delivery system “Clip Holder” is an indispensable technology for vascular and heart surgeons. This is a clip from an alloy with a direct and reversible shape memory metal and delivery mechanisms for temporary or permanent imposition of vessels or arteries, allowing the attachment and removal of the belt clip without damaging blood vessels.

The hyperelastic "Tral" trap allows the speedy removal of foreign bodies from hollow organs and tubular structures. For example, it can be used to remove foreign bodies from the trachea andstones from the gall bladder and the ureter as well as to find and get rid of the clots in vessels. The main difference from existing analogues is the ease of use and the possibility to release a foreign body when it has been captured from the wrong side. This tool will be especially in demand in first aid.

The project, implemented by MIS&S in cooperation with Australian partners, was launched in 2010, and now it is heading into the homestretch and commercialization stage: numerous bench and clinical trials on animals have been successfully completed; the producers in Russia and Taiwan have been identified, a pilot production of the staple, “Tral,” and “Clip Holder” have started, and waste production of shape memory metal has been prepared.